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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRE
All Species:
29.39
Human Site:
Y539
Identified Species:
71.85
UniProt:
P23469
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23469
NP_006495.1
700
80642
Y539
E
Q
D
K
C
Y
Q
Y
W
P
T
E
G
S
V
Chimpanzee
Pan troglodytes
XP_001141616
700
80579
Y539
E
Q
D
K
C
Y
Q
Y
W
P
T
E
G
S
V
Rhesus Macaque
Macaca mulatta
XP_001114682
793
89729
Y637
G
Q
E
K
C
A
Q
Y
W
P
S
D
G
L
V
Dog
Lupus familis
XP_852697
701
80587
Y540
E
Q
D
K
C
Y
Q
Y
W
P
T
E
G
S
V
Cat
Felis silvestris
Mouse
Mus musculus
P49446
699
80669
Y538
E
Q
D
K
C
Y
Q
Y
W
P
T
E
G
S
V
Rat
Rattus norvegicus
Q03348
796
90242
Y640
G
Q
E
K
C
A
Q
Y
W
P
S
D
G
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516836
648
74144
V519
D
E
C
E
S
Y
T
V
R
D
L
L
V
T
N
Chicken
Gallus gallus
XP_421821
737
84857
Y576
E
Q
E
K
C
F
Q
Y
W
P
S
E
G
S
V
Frog
Xenopus laevis
NP_001089394
819
92510
Y663
G
Q
E
K
C
S
Q
Y
W
P
S
E
G
T
I
Zebra Danio
Brachydanio rerio
XP_695831
634
73247
L505
T
L
C
E
T
F
S
L
R
D
L
V
L
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
60.4
94.2
N.A.
93
59.1
N.A.
62.5
80.8
58.9
72.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
72.6
97
N.A.
96.7
72.7
N.A.
75.7
87.2
71.7
81.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
60
100
N.A.
100
60
N.A.
6.6
80
60
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
80
N.A.
33.3
100
86.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
20
0
80
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
40
0
0
0
0
0
0
20
0
20
0
0
0
% D
% Glu:
50
10
40
20
0
0
0
0
0
0
0
60
0
0
0
% E
% Phe:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
80
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
0
20
10
10
20
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% P
% Gln:
0
80
0
0
0
0
80
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
10
0
0
0
40
0
0
50
0
% S
% Thr:
10
0
0
0
10
0
10
0
0
0
40
0
0
30
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
70
% V
% Trp:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _